During his time at MGM studios, Buster Keaton's career took a downturn, primarily due to the loss of creative control over his projects. The studio's strict management style stifled his artistic freedom, leading to less inspired films that failed to connect with audiences. Additionally, the introduction of talkies changed the landscape of comedy, and Keaton struggled to adapt his silent film techniques to this new format. Other factors, such as his personal struggles with alcoholism and a series of failed marriages, further complicated his career at MGM. Ultimately, these factors combined to result in Keaton's failure at the iconic studio.